BIOMATERIALS NOTES
ANNA UNIVERSITY
2017 REGULATION
Syballus:
UNIT I INTRODUCTION TO BIO-MATERIALS
Definition and classification of bio-materials, mechanical properties, visco elasticity, biomaterial performance, body response
to implants, wound healing, blood compatibility, Nano scale phenomena.
UNIT II METALLIC AND CERAMIC MATERIALS
Metallic implants - Stainless steels, co-based alloys, Ti-based alloys, shape memory alloy, nanostructured metallic implants,
degradation and corrosion, ceramic implant – bio inert, biodegradable or bioresorbable, bioactive ceramics, nanostructured
bio ceramics.
UNIT III POLYMERIC IMPLANT MATERIALS
Polymerization, factors influencing the properties of polymers, polymers as biomaterials, biodegradable polymers, Bio
polymers: Collagen, Elastin and chitin. Medical Textiles, Materials for ophthalmology: contact lens, intraocular lens.
Membranes for plasma separation and Blood oxygenation, electro spinning: a new approach.
UNIT IV TISSUE REPLACEMENT IMPLANTS
Small intestinal sub mucosa and other decullarized matrix biomaterials for tissue repair: Extra cellular Matrix. Softtissue
replacements, sutures, surgical tapes, adhesive, Percutaneous and skin implants, maxillofacial augmentation, Vascular grafts,
hard tissue replacement Implants, joint replacements, tissue scaffolding and engineering using Nano biomaterials.
UNIT V TESTING OF BIOMATERIALS
Biocompatibility, blood compatibility and tissue compatibility tests, Toxicity tests, sensitization, carcinogenicity,
mutagenicity and special tests, Invitro and Invivo testing; Sterilisation of implants and devices: ETO, gamma radiation,
autoclaving. Effects of sterilization
2marks notes: click here
Unit 1 to Unit 5 notes: click here
Books: click here
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