BIOCONTROL SYSTEMS BM8501
AU Regulation 2017
Syballus
OBJECTIVES
The student should be made:
To understand the concept behind feedback and continuum in various systems and subsystems.
To analyse the systems in time and frequency domain and to understand the concept of stability
To apply mathematical modelling principles in understanding the various fundamental biological
systems
To analyse biological system models using MATLAB
UNIT I INTRODUCTION
Open and Closed loop Systems, Modeling and Block Diagrams, Block diagram and signal flow graph
representation of systems, reduction of block diagram and signal flow graph, Introduction to
Physiological control systems- Illustration, Linear models of physiological systems, Difference between
engineering and physiological control system.
UNIT II TIME RESPONSE ANALYSIS
Step and impulse responses of first order and second order systems, time domain specifications of first
and second order systems, steady state error constants, Definition of stability, Routh- Hurwitz criteria of
stability, root locus technique, construction of root locus and study of stability.
UNIT III FREQUENCY RESPONSE ANALYSIS
Frequency domain specifications - Polar plots, Bode plots, Nyquist plot, Nyquist stability criterion, closed
loop stability, Constant M and N circles, Nichol‘s chart.
UNIT IV BIOLOGICAL SYSTEM MODELS
Distributed parameter versus lumped parameter models, Model development of Cardiovascular system-
Heart model-circulatory model, Pulmonary mechanics- Lung tissue visco-elastance-chest wall- airways,
Interaction of Pulmonary and Cardiovascular models, Static analysis of physiological systems –
Regulation of cardiac output, Regulation of ventilation.
UNIT V BIOLOGICAL CONTROL SYSTEM ANALYSIS
Simple models of muscle stretch reflex action, Study of steady state analysis of muscle stretch reflex
action, Study of transient response analysis of neuromuscular reflex model action, Study of frequency
response of circulatory control model, Stability analysis of Pupillary light reflex.
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