BIOCONTROL SYSTEMS BM8501 NOTES

BIOCONTROL SYSTEMS BM8501

AU Regulation 2017

Syballus

OBJECTIVES

The student should be made:

To understand the concept behind feedback and continuum in various systems and subsystems.

To analyse the systems in time and frequency domain and to understand the concept of stability

To apply mathematical modelling principles in understanding the various fundamental biological

systems

To analyse biological system models using MATLAB

UNIT I INTRODUCTION

Open and Closed loop Systems, Modeling and Block Diagrams, Block diagram and signal flow graph

representation of systems, reduction of block diagram and signal flow graph, Introduction to

Physiological control systems- Illustration, Linear models of physiological systems, Difference between

engineering and physiological control system.

UNIT II TIME RESPONSE ANALYSIS

Step and impulse responses of first order and second order systems, time domain specifications of first

and second order systems, steady state error constants, Definition of stability, Routh- Hurwitz criteria of

stability, root locus technique, construction of root locus and study of stability.

UNIT III FREQUENCY RESPONSE ANALYSIS

Frequency domain specifications - Polar plots, Bode plots, Nyquist plot, Nyquist stability criterion, closed

loop stability, Constant M and N circles, Nichol‘s chart.

UNIT IV BIOLOGICAL SYSTEM MODELS

Distributed parameter versus lumped parameter models, Model development of Cardiovascular system-

Heart model-circulatory model, Pulmonary mechanics- Lung tissue visco-elastance-chest wall- airways,

Interaction of Pulmonary and Cardiovascular models, Static analysis of physiological systems –

Regulation of cardiac output, Regulation of ventilation.

UNIT V BIOLOGICAL CONTROL SYSTEM ANALYSIS

Simple models of muscle stretch reflex action, Study of steady state analysis of muscle stretch reflex

action, Study of transient response analysis of neuromuscular reflex model action, Study of frequency

response of circulatory control model, Stability analysis of Pupillary light reflex.

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