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Biomedical instrumentation BM8502 Syballus

 Syllabus

BM8502 BIOMEDICAL INSTRUMENTATION 


OBJECTIVES:

The students will be exposed to electrical and non-electrical physiological measurements and

bioamplifiers.

UNIT I BIO POTENTIAL ELECTRODES 

Origin of bio potential and its propagation. Electrode-electrolyte interface, electrode–skin interface, half

cell potential, Contact impedance, polarization effects of electrode – non polarizable electrodes. Types of

electrodes - surface, needle and micro electrodes and their equivalent circuits. Recording problems –

motion artifacts, measurement with two electrodes.

UNIT II BIOPOTENTIAL MEASUREMENTS 

Biosignals characteristics – frequency and amplitude ranges. ECG – Einthoven’s triangle, standard 

lead system, Principle of vector cardiography, EEG – 10-20 electrode system, unipolar, bipolar and

average mode.EMG– unipolar and bipolar mode, Recording of ERG, EOG and EGG.

UNIT III SIGNAL CONDITIONING CIRCUITS 

Need for bio-amplifier - single ended bio-amplifier, differential bio-amplifier Impedance matching

circuit, isolation amplifiers- Transformer and optical isolation– isolated DC amplifier and AC carrier

amplifier, Power line interference, Right leg driven ECG amplifier, Band pass filtering

UNIT IV MEASUREMENT OF NON-ELECTRICAL PARAMETERS 

Temperature, respiration rate and pulse rate measurements. Blood Pressure: indirect methods -

auscultatory method, oscillometric method, direct methods: electronic manometer, Pressure amplifiers -

systolic, diastolic, mean detector circuit. Blood flow and cardiac output measurement: Indicator

dilution, thermal dilution and dye dilution method, Electromagnetic and ultrasound blood flow

measurement.

UNIT V BIO-CHEMICAL MEASUREMENT AND BIOSENSOR 

Biochemical sensors - pH, pO2 and pCO2, Ion selective Field effect Transistor (ISFET),

Immunologically sensitive FET (IMFET), Blood glucose sensors - Blood gas analyzers, colorimeter-

sodium potassium analyzer, spectrophotometer, blood cell counter, auto analyzer (simplified schematic

description), Bio sensors- Principles- amperometric and voltometric techniques 


For notes - visit here


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